Clinical trial

Periodontal Microbiota of Patients Candidates for Bariatric Surgery With Body Mass Index Greater Than 30

Recruiting now · Not applicable · 1 countries · Registry ID NCT06781229

Recruiting nowNot applicableObservational

What this study is about

The goal of this observational study is to compare the microbiological composition of the periodontal plaque of obese people undergoing bariatric surgery according to their Body Mass Index. The main question it aims to answer is: Does obese patients have different microbiote according to their obesity? Obesity being classified in two groups : * group "obesity" for a BMI between 30 and 35 * versus "morbid obesity" group with a BMIabove 35. Participants who are scheduled to undergo bariatric surgery as part of their regular medical care will answer questions about their quality of life, hygiene habits, and saliva and periodontal samples will be taken.

A promising-looking record is not the same as confirmed eligibility. The study team must review the full criteria and current recruitment status.

Basic eligibility

Age18 Years to Not listed

SexAll

Healthy volunteersNot accepted

ConditionBariatric Surgery, Obesity, Morbid

Full registry criteria

Inclusion Criteria: * BMI greater than or equal to 30 * Be on the list of patients scheduled for bariatric surgery, * Be able to receive information about the study and understand the information form in order to take part in the study. This implies mastering the French language, Exclusion Criteria: * Alcohol consumption \>30g/d (men) or 20g/d (women), * Having taken antibiotics, prebiotics or probiotics in the month prior to inclusion (this has an influence on the composition of the patient's microbiota), * During pregnancy or breastfeeding, * For whom oral surgery is planned (surgery for benign or malignant tumours of the maxillary and mandibular bone bases), or with a history of oral surgery in the month prior to inclusion, * At risk of infection (existence of one or more of the following known chronic infectious diseases: HIV, HBV, HCV and mononucleosis) and/or chronic renal insufficiency (creatinine clearance \< 60ml/min), * Patients with a general pathology that contraindicates the performance of diagnostic procedures such as periodontal probing (patients at high risk of infective endocarditis according to the ANSM). * Totally edentulous patients

Treatments and study arms

The registry does not list a named intervention.

Primary outcomes

Taxonomic analysisbefore bariatric surgery

Taxonomic analysis of the microbiological composition of the periodontal plaque between group 1 (obesity) and 2 (morbid obesity) : relative quantities of periodontal bacteria between group 1 (obesity) and 2 (morbid obesity)

Study locations

1 locations were listed when this page was built. The first 40 are shown.

University Hospital of Toulouse🇫🇷 Toulouse, France

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