Clinical trial
Wild Blueberries for Gut, Brain, and Heart Health in Adults With High Blood Pressure
Recruiting now · Not applicable · 1 countries · Registry ID NCT06735599
Recruiting nowNot applicableInterventional
What this study is about
The purpose of the study is to determine the effectiveness of wild blueberries on cardiovascular health, cognitive function, and gut microbiota composition in non-Hispanic Black and White adults with elevated blood pressure.
A promising-looking record is not the same as confirmed eligibility. The study team must review the full criteria and current recruitment status.
Basic eligibility
Age45 Years to 65 Years
SexAll
Healthy volunteersNot accepted
ConditionHypertension (Without Type 2 Diabetes Mellitus), High Blood Pressure, Male, Female, Adult, Cognition, Endothelial Function (Reactive Hyperemia), Oxidative Stress, Diet, Overweight, Body Composition Measurement, Gut Microbiome, Arterial Stiffness, Caucasian Whites, Inflammation, Microvascular Function
Full registry criteria
Inclusion Criteria: * Individuals 45-65 years of age * Diagnosis of elevated blood pressure or stage 1 hypertension (systolic blood pressure = 120-139 mmHg and/or diastolic blood pressure = 80-89 mmHg) for at least 6 months * BMI 25-35 kg/m2 via anthropometric measurements. * Ability to give consent Exclusion Criteria: * Allergies to berries * Use of one hypertensive drug for less than three months * Use of more than one anti-hypertensive or statin drug, insulin, antibiotics, and anti-inflammatory drugs, active cancer, gastrointestinal, renal, cardiovascular, thyroid, and neurological disorders or severe head injury * Smoking * Alcohol consumption (\>2 drinks/day) * Consuming antioxidant, probiotic, and prebiotic supplements * Pregnant or lactating * Participating in a weight loss program
Treatments and study arms
Wild Blueberry
Dietary Supplement
Daily consumption of 22 g of freeze-dried wild blueberry freeze-dried powder for 8 weeks
Placebo
Dietary Supplement
Daily consumption of 22 g of freeze-dried macronutrient-matched placebo powder for 8 weeks
Primary outcomes
Ambulatory Blood PressureBaseline, 4 weeks, and 8 weeks
Assessment of whole-day ambulatory blood pressure during daytime and nighttime periods.
Pulse Wave VelocityBaseline, 4 weeks, and 8 weeks
Arterial Stiffness will be measured by pulse wave velocity using SphygmCor
Study locations
1 locations were listed when this page was built. The first 40 are shown.
Georgia State University🇺🇸 Atlanta, Georgia, United States
Rafaela Feresin, PhDContact
Rafaela G Feresin, PhDPrincipal Investigator
Andrew Gerwitz, PhDSub Investigator