Clinical trial

Diet Intervention on Obesity Related Complication

Active, not recruiting · Not applicable · 1 countries · Registry ID NCT06719466

Active, not recruitingNot applicableInterventional

What this study is about

Obesity has become a global epidemic, with more than 4 billion people expected to be overweight/obese by 2035, accounting for more than half of the world's population. Currently, there are sixteen recognized complications directly related to obesity, including gastroesophageal reflux disease. In recent years, people have increasingly paid attention to the damage caused by obesity to the stomach. In addition to gastroesophageal reflux disease, obesity also leads to various forms of gastric mucosal damage related diseases, such as gastric ulcers, chronic gastritis, intestinal metaplasia, and so on. This stuty aimed to observe the diet intervention on obesity related stomach.

A promising-looking record is not the same as confirmed eligibility. The study team must review the full criteria and current recruitment status.

Basic eligibility

Age18 Years to 65 Years
SexAll
Healthy volunteersNot accepted
ConditionObese, Stomach Diseases

Full registry criteria

Inclusion Criteria: 1. Obtain informed consent before carrying out any trial-related activity, which is any procedure carried out as part of a trial, including the identification of activities suitable for the trial 2. Men and premenopausal women, ages 18-65 at the time of signing the informed consent form 3. Obese patients are diagnosed based on a body mass index (BMI) of 28-40kg/m2 Exclusion Criteria: 1)Patients who do not possess or lose the ability to make their judgment, are unable to understand the purpose of the study, or are unwilling to cooperate with it; 2) Heart, liver, kidney dysfunction,and systemic diseases, such as various malignant tumors, systemic allergic diseases, and autoimmune diseases; 3)Drug or alcohol dependence, intellectual disability, mental disorders; 4)Pregnant and lactating women; 5) Confirmed Helicobacter pylori infection (PPI, bismuth, and antibiotics were stopped for at least 4 weeks, and any of the following tests were positive: non-invasive HP test such as urea breath test, monoclonal stool Helicobacter pylori antigen test, serum soluble Helicobacter pylori antigen test; Invasive Hp test included rapid urease test and tissue section staining); 6)diagnosis of acute gastric mucosal lesions; 7)the patient was diagnosed with chronic gastritis according to the new Sydney system visual simulation scoring method and the pathological diagnostic criteria of chronic gastritis in China; 8) histological and imaging examinations, adenocarcinoma was diagnosed.

Treatments and study arms

low linoleic acid (LA)

Other

diet guidance with low linoleic acid (LA) diet

Primary outcomes

body weight12 weeks

stomach injury scale

Study locations

1 locations were listed when this page was built. The first 40 are shown.

Department of Endocrinology, Shanghai Tenth People's Hospital🇨🇳 Shanghai, China