Clinical trial

Predictive Effect of Abdominal Fat and Muscle Area Calculated Based on Abdominal CT on Colorectal Cancer Patients

Active, not recruiting · Not applicable · 1 countries · Registry ID NCT06614699

Active, not recruitingNot applicableObservational

What this study is about

This study aims to create a clinical prediction model. Abdominal fat and muscle area also play an important role in the prediction of surgical outcomes in colorectal cancer. Studies have shown that excess visceral fat and low skeletal muscle mass (sarcopenia) are associated with poorer postoperative outcomes, including a higher risk of postoperative complications and lower survival. Preoperative imaging techniques such as CT, MRI and ultrasound that provide accurate measurements to assess abdominal fat and muscle area can help surgeons develop individualized surgical and rehabilitation plans, improve surgical success, reduce complications and improve long-term patient prognosis. In this study, the investigators expected to construct a prediction model of abdominal fat and muscle area on the short- and long-term outcomes of colorectal cancer patients by calculating the abdominal fat and muscle area in different levels of abdominal CT images, in order to further adjust and guide the treatment plan.

A promising-looking record is not the same as confirmed eligibility. The study team must review the full criteria and current recruitment status.

Basic eligibility

Age18 Years to Not listed
SexAll
Healthy volunteersNot accepted
ConditionColorectal Cancer, Sarcopenia, Obesity and Overweight

Full registry criteria

Inclusion Criteria: * 1, Diagnosis of colorectal cancer confirmed by pathology or cytology; * 2, aged \>18 years; * 3, not received chemotherapy, radiotherapy, targeted therapy or immunotherapy; * 4, post-operative pathological stages other than stage IV, or no liver, lung or other organs as confirmed by CT, MRI, B-ultrasound imaging. * 5, patients who have pre-operative CT examination data kept in our hospital. Exclusion Criteria: * 1, Poor quality of preoperative CT images; * 2, refusal to participate in this study.

Treatments and study arms

abdominal fat and muscle area

Other

Abdominal fat and muscle area were calculated based on abdominal CT.

Primary outcomes

Overall survivalFrom date of diagnosis until the date of death from any cause or or loss to follow-up, whichever came first, assessed up to 60 months.

Overall survival was defined as time from date of diagnosis until the date of death from any cause or or loss to follow-up.

Study locations

3 locations were listed when this page was built. The first 40 are shown.

The Affiliated Yongchuan Hospital of Chongqing Medical University🇨🇳 Chongqing, Chongqing Municipality, China
The First Affiliated Hospital of Chongqing Medical University🇨🇳 Chongqing, Chongqing Municipality, China
The Second Affiliated Hospital of Chongqing Medical University🇨🇳 Chongqing, Chongqing Municipality, China