Clinical trial
Pharmacokinetics of Drospirenone Only Pills: A Pre- and Post-Bariatric Surgery Study
Recruiting now · Phase 1, Phase 2 · 1 countries · Registry ID NCT06345560
Recruiting nowPhase 1, Phase 2Interventional
What this study is about
The purpose of this study is to investigate whether bariatric surgery affects Drospirenone only pills absorption
A promising-looking record is not the same as confirmed eligibility. The study team must review the full criteria and current recruitment status.
Basic eligibility
Age18 Years to 45 Years
SexFemale
Healthy volunteersNot accepted
ConditionContraception
Full registry criteria
Inclusion Criteria: * Thai women aged 18-45 years who are obese and had an appointment for Bariatric surgery at Chulalongkorn Hospital * Need contraception * Able to use non-hormonal contraception during the study * Giving consent Exclusion Criteria: * Pregnancy or history of giving birth within 3 months * Breastfeeding within the 6 months * History of using DMPA within 12 months * History of using other types of hormonal birth control pills within 4 weeks * History of bilateral oophorectomy or hysterectomy * Suspected ovarian tumor or pathological ovarian cyst * Regular cigarette smoking * Contraindications to Drospirenone
Treatments and study arms
Drospirenone
Drug
4 mg tablet once daily
Primary outcomes
Plasma concentration versus Time of Drospirenone1 month before and 1 month after bariatric surgery
Plasma concentration of Drospirenone will be measured at 0, 0.5, 1, 1.5, 2, 2.5, 3, 3.5, 4, 4.5, 5, 5.5, 6, 8 hours post-dose
Study locations
1 locations were listed when this page was built. The first 40 are shown.