Recruiting nowNot applicableInterventional
What this study is about
LIMITFOOD2 is a randomized clinical intervention study that investigates the effects of two different intermittent fasting protocols compared to a control group on the health of obese adults. A total of 90 participants will be randomized into three equally sized groups: a modified alternate day fasting, a time-restricted eating and a control group, receiving general weight-loss counseling.
A promising-looking record is not the same as confirmed eligibility. The study team must review the full criteria and current recruitment status.
Basic eligibility
Age18 Years to 50 Years
SexAll
Healthy volunteersAccepted
ConditionIntermittent Fasting, Obesity, Time Restricted Eating
Full registry criteria
Inclusion Criteria: * Age between 18-50 years, both inclusive * Obese, BMI between 30 and 40 kg/m\^2 (obesity grade I or II), both inclusive * Non-smoker * Good knowledge of German or English language * Stable weight change (change \< +/- 3% current bodyweight) for 3 months prior to the study * HbA1c \< 6.5% without glucose lowering medication * LDL-cholesterol \< 4.6mmol/l without lipid lowering medication Exclusion Criteria: * Participants who have a fasting period of \> 12h per day on a regular basis and do not eat at least three main meals per day. * Current habitual use of dietary supplements (e.g., vitamins, minerals) and/or unwillingness to cease intake of dietary supplements. * Antibiotics intake during 3 months prior to the study due to possible interference with metabolic parameters * Food intolerances, allergies and sensitivities (severe food allergies) or dietary restrictions (e.g. vegan lifestyle) * Acute or chronic infections, malignant disease, renal, hepatic (more than two-fold increased transaminases), pulmonary, neurological (epilepsy) or psychiatric diseases, manifested atherosclerosis, or any other disease precluding participation in the study. * Diabetes * Known alcohol, substance or drug abuse, concomitant medication * More than four hours of physical exercise per week * Women who are pregnant, breast-feeding or aiming to become pregnant during course of the trial * Women and men on hormonal supplementation * Women with an irregular menstrual cycle according to the FIGO criteria * Therapy with antidepressants within the past 6 months * Regular therapy with acetylsalicyclic acid or current medication to regulate blood sugar, blood pressure or lipids * Participants likely to fail to comply with the study protocol * Participants who do not give informed consent
