Clinical trial

Weight Loss and ExeRcise for Post-stroke Veterans

Recruiting now · Not applicable · 1 countries · Registry ID NCT06322030

Recruiting nowNot applicableInterventional

What this study is about

Weight loss interventions for neurologically health individuals have established benefits for improving physical and psychosocial function. The investigators believe that Veterans who have had a stroke would realize similar benefits and that the effects would be enhanced with concurrent exercise training. The investigators will study the effects of a 15-week lifestyle management program to determine if it can effectively improve some of the physical and psychosocial problems common in Veterans who have had a stroke.

A promising-looking record is not the same as confirmed eligibility. The study team must review the full criteria and current recruitment status.

Basic eligibility

Age40 Years to 80 Years

SexAll

Healthy volunteersNot accepted

ConditionStroke

Full registry criteria

Inclusion Criteria: * A diagnosis of stroke at least 6 months prior * BMI \> 30 kg/m2 * Residual paresis in the lower extremity (Fugl-Meyer LE motor score \<34) * Ability to follow instructions, complete training and testing and to communicate exertion, pain and distress * Provision of informed consent * Individuals who meet inclusion criteria must complete an exercise tolerance test and be cleared for participation by the study cardiologist Exclusion Criteria: * Unable to ambulate at least 150 feet or experienced intermittent claudication while walking * Unstable cardiac arrhythmias, hypertrophic cardiomyopathy, severe aortic stenosis, angina or dyspnea at rest or during ADL's * Dementia * Life expectancy \<1 yr * History of DVT or pulmonary embolism within 6 months * Uncontrolled diabetes with recent weight loss, diabetic coma, or frequent insulin reactions * Severe hypertension with systolic \>200 mmHg and diastolic \>110 mmHg at rest * Current enrollment in a rehabilitation trial to enhance motor or psychosocial recovery

Treatments and study arms

FOCUS-15 Lifestyle Management Program

Dietary Supplement

15 week weight management program

Exercise Training

Behavioral

15 weeks of progressive exercise training

Primary outcomes

Change in distance walk in 6 minute Walk Testapproximately 15 weeks

Distance walk in 6 minutes

Study locations

1 locations were listed when this page was built. The first 40 are shown.

Ralph H. Johnson VA Medical Center, Charleston, SC🇺🇸 Charleston, South Carolina, United States

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R. Amanda C LaRue, PhDContact

Email · Call 843-789-6707

Thad Abrams, MDContact

Email · Call (319) 338-0581

Chris M Gregory, PhDPrincipal Investigator