Clinical trial
A Study of RAY1225 in Participants With Obesity
Recruiting now · Phase 2 · 1 countries · Registry ID NCT06254261
Recruiting nowPhase 2Interventional
What this study is about
The main purpose of this study is to learn more about the Tolerability of RAY1225 in participants with Obesity. The study will also explore the efficacy of RAY1225. The study will last about six months for each participant.
A promising-looking record is not the same as confirmed eligibility. The study team must review the full criteria and current recruitment status.
Basic eligibility
Age18 Years to 70 Years
SexAll
Healthy volunteersNot accepted
ConditionObesity
Full registry criteria
Inclusion Criteria: 1. Have a body mass index (BMI) of ≥28 kilogram per square meter (kg/m²) or ≥24 kg/m² and previously diagnosed with at least one of the following weight related comorbidities: hypertension, dyslipidemia, obstructive sleep apnea, fatty liver disease,or HbA1c ≥5.7% and \< 6.5%; 2. Participants (including partners) must use reliable methods of contraception during the study and until 6 months following the last dose of investigational product. Exclusion Criteria: 1. Obesity induced by other endocrinologic disorders or monogenetic or syndromic forms of obesity 2. with a history of diabetes or hypoglycemia; 3. Have a family or personal history of medullary thyroid carcinoma (MTC) or Multiple Endocrine Neoplasia (MEN) Syndrome type 2 or with thyroid nodules of unknown etiology found at screening and considered clinically significant by the investigator. 4. Have a prior or planned surgical treatment for obesity (excluding liposuction or abdominoplasty if performed \>1 year prior to screening) 5. allergic constitution; 6. not suitable for subcutaneous injection.
Treatments and study arms
RAY1225
Drug
Administered SC
Placebo
Drug
Placebo
Primary outcomes
Change From Baseline in Body WeightBaseline,Week26
Percent Change from Baseline in Body Weight
Study locations
1 locations were listed when this page was built. The first 40 are shown.
Peking University People's Hospital🇨🇳 Beijingcun, Hebei, China
JI, professorContact