Clinical trial

Polycystic Ovary Syndrome, Mitochondrial Dysfunction, Obesity, Insulin Resistance Infertility (POMODORI) Cohort

Recruiting now · Not applicable · 1 countries · Registry ID NCT06167135

Recruiting nowNot applicableObservational

What this study is about

Enrolling of 150 female patients of fertile age diagnosed with PCOS, insulin resistance, infertility, or mitochondrial disease, and the same number of age- and sex-matched controls are planned. During the research biomarkers already with mitochondrial dysfunction in the scientific literature and common mtDNA abnormalities (deletions, point mutations, copy number changes, etc.) are examined.

A promising-looking record is not the same as confirmed eligibility. The study team must review the full criteria and current recruitment status.

Basic eligibility

Age20 Years to 45 Years

SexFemale

Healthy volunteersAccepted

ConditionInfertility, Female, Polycystic Ovary Syndrome, Insulin Resistance, Primary Ovarian Insufficiency, Mitochondrial Alteration, Obesity

Full registry criteria

Inclusion Criteria: * Presence of polycystic ovary syndrome (PCOS) or insulin resistance (IR) associated with other multisystemic phenotypes, mitochondrial dysfunction * history of infertility associated with other multisystemic phenotypes, mitochondrial dysfunction * a known history of mitochondrial dysfunction and PCOS and/or IR * general health is good and there is no serious general medical condition that would prevent participation would make participation highly risky Exclusion Criteria: * poor cooperation * refusal to participate in the study

Treatments and study arms

The registry does not list a named intervention.

Primary outcomes

Serum Glucose and Insulin LevelsOne year

The serum glucose and insulin levels are calculated by using plasma concentrations of insulin and glucose obtained during 120 min of a standard (75 g glucose) OGTT. Fasting, 1h and 2h glucose and insulin levels are measured

Clinical Pregnancy RateOne year

Clinical pregnancy rate = the number of clinical pregnancies/the total number of participants in the patient cohort × 100%

Study locations

1 locations were listed when this page was built. The first 40 are shown.

Semmelweis University🇭🇺 Budapest, Hungary

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Vera Várhegyi, MDContact

Email · Call +36206663493

Anikó Gál, PhDContact

Email · Call +36206632516