Clinical trial

Analysis of Varus Collapse in Obese Patients With Stem and Non-Stem Tibial Components Following Primary Total Knee Arthroplasty

Active, not recruiting · Not applicable · 1 countries · Registry ID NCT06019832

Active, not recruitingNot applicableInterventional

What this study is about

The purpose of this study is to compare rates of varus collapse, aseptic loosening, and implant failure in female obese patients undergoing total knee arthroplasty (TKA) and will review the degree of influence of stemmed tibial components versus non-stemmed tibial components on varus collapse and aseptic loosening, a consequence of implant micromotion.

A promising-looking record is not the same as confirmed eligibility. The study team must review the full criteria and current recruitment status.

Basic eligibility

Age40 Years to 99 Years
SexFemale
Healthy volunteersNot accepted
ConditionObesity, Aseptic Loosening, Varus Collapse

Full registry criteria

Inclusion criteria: * Female adult patients with severe osteoarthritis scheduled to have primary total knee arthroplasty * Age 40 or older * 35 kg/m2 and above * Only patients from the PI's clinic will be included. * Women who are still menstruating and are currently on contraceptives and women who are in menopause. Exclusion Criteria: * Patients who have some active local or widespread infection (including secondary or inflammatory osteoarthritis) * medical conditions that put them at risk of complications or death during and after the study would not be eligible for surgery * Patients with previous knee surgery on arthroplasty site will be excluded * Pregnant patients and women who are capable of getting pregnant

Treatments and study arms

Total Knee Arthroplasty (TKA)

Procedure

Both study arms will undergo TKA

Stemmed Tibial Implant

Device

A stemmed tibial implant.

Non-stemmed tibial implant

Device

A non-stemmed tibial implant.

Primary outcomes

Varus Collapseup to 5 years post surgery

The investigators will track rate of varus collapse.

Aseptic looseningup to 5 years post surgery

The investigators will track rates of aseptic loosening.

Study locations

1 locations were listed when this page was built. The first 40 are shown.

Iowa Health Care Medical Center North Liberty🇺🇸 North Liberty, Iowa, United States