Clinical trial

Effect of Obesity, Diabetes and Bariatric Surgery on Pregnancy Outcomes

Recruiting now · Not applicable · 1 countries · Registry ID NCT05753124

Recruiting nowNot applicableObservational

What this study is about

The obesity epidemic is growing worldwide and in the UK this is perpetuated with a third of women classified as overweight/obese in 2020. Many of these woman are of childbearing age and go on to have high risk pregnancies which are often complicated by gestational or pre-existing (type 2 diabetes mellitus (GDM, T2DM). Bariatric surgery is the most successful treatment of sustainable weight loss and is associated with a reduction in rates of GDM, pre-eclampsia, delivery of large babies but increased risk of delivery of small babies and preterm delivery. The aims of the study are to investigate the maternal and fetal/neonatal, biophysical and biochemical, intra-uterine environment and postnatal profile of pregnancies: 1. affected by maternal obesity and/or GDM/T2DM compared to pregnancies with normal maternal body mass index (BMI). 2. with previous maternal bariatric surgery compared to pregnancies without previous bariatric surgery but matched for maternal pre-surgery and early pregnancy BMI.

A promising-looking record is not the same as confirmed eligibility. The study team must review the full criteria and current recruitment status.

Basic eligibility

Age18 Years to 50 Years

SexFemale

Healthy volunteersAccepted

ConditionObesity, Pregnancy in Diabetic, Pregnancy Complications, Pregnancy Related, Bariatric Surgery Status Complicating Pregnancy

Full registry criteria

Inclusion Criteria: * Pregnant women with normal size (BMI \<30) * Pregnant women with obesity (BMI ≥30) * Pregnant women with glucose disorders * Pregnant women with previous bariatric surgery Exclusion Criteria: * Pregnant women less than 18 years of age * Pregnant women with twins/triplets

Treatments and study arms

Observational

Other

This is an observational study

Primary outcomes

Birth weight (in percentiles)At the time of birth

Birthweight percentiles will be compared in the groups studied

Study locations

1 locations were listed when this page was built. The first 40 are shown.

Chelsea & Westminster Hospital Nhs Ft🇬🇧 London, United Kingdom

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MAKRINA SAVVIDOU, MDContact