Clinical trial
Predictors of Behavioral Obesity Treatment Outcomes
Recruiting now · Not applicable · 1 countries · Registry ID NCT05326477
Recruiting nowNot applicableInterventional
What this study is about
Socioceconomically disadvantaged individuals typically have poor outcomes in behavioral weight loss interventions, but the reasons for this are unknown. This project will characterize the mechanisms through which adverse daily experiences and present bias -- a cognitive adaptation to harsh and unpredictable environments -- account for disparities in weight loss outcomes.
A promising-looking record is not the same as confirmed eligibility. The study team must review the full criteria and current recruitment status.
Basic eligibility
Age18 Years to Not listed
SexAll
Healthy volunteersAccepted
ConditionObesity
Full registry criteria
Inclusion Criteria: 1. Age ≥18 years old 2. Obesity (body mass index ≥30 kg/m2) 3. Meets criteria for either the lower SES or higher SES cohort Exclusion Criteria: 1. Not fluent in English 2. Change in income or financial assets exceeding ±75% of federal poverty guideline within the past 12 months, or expected in the next 6 months, if this change would result in reclassification on SES. 3. Previous or planned bariatric surgery, or concurrent engagement in other behavioral or pharmacological treatment for obesity 4. Resides more than 20 miles away from Rush, or planning to move outside of this geographic area during the study period 5. Body mass index ≥60 kg/m2, due to increased injury risk with exercise 6. History of bariatric surgery, or current engagement in another weight loss therapy 7. Lack of reliable access to cell or landline phone 8. Medical contraindications to treatment, including osteoporosis, cognitive impairment (Montreal Cognitive Assessment ≤25), active substance abuse based on the World Health Organization's ASSIST screener, lack of physician clearance for participation, or serious medical illness (e.g., stage 3 or 4 heart failure, cancer, renal failure, etc.)
Treatments and study arms
Behavioral weight loss treatment
Behavioral
The weight loss intervention consists of the first 6 months of the Centers for Disease Control and Prevention's Prevent T2 program.
Primary outcomes
Weight changeMonths 2, 4, and 6
Weight change, reported as a percentage of baseline weight
Study locations
1 locations were listed when this page was built. The first 40 are shown.
Rush University Medical Center🇺🇸 Chicago, Illinois, United States
Michele Li, MS, RDContact
Bradley M Appelhans, PhDPrincipal Investigator