Clinical trial
Optimal Management of Extreme Obesity and Severe Knee Osteoarthritis Feasibility Trial
Recruiting now · Not applicable · 1 countries · Registry ID NCT05120492
Recruiting nowNot applicableInterventional
What this study is about
Does weight loss surgery in patients with morbid obesity prior to knee replacement surgery improve outcomes from knee replacement surgery
A promising-looking record is not the same as confirmed eligibility. The study team must review the full criteria and current recruitment status.
Basic eligibility
Age18 Years to 65 Years
SexAll
Healthy volunteersAccepted
ConditionKnee Osteoarthritis, Morbid Obesity
Full registry criteria
Inclusion Criteria: severe knee osteoarthritis body-mass index of 45 to 60 Exclusion Criteria: previous total replacement of the same knee, a need for bilateral total knee replacement, and knee pain during the previous week that the patient rated at higher than 60 mm on a 100-mm visual-analogue scale. Also,prior bariatric or complex foregut surgery, significant cardiovascular, pulmonary, renal, liver, gastrointestinal, psychiatric disorders, pregnancy, malignancy within last 5 years, anemia, coagulopathy requiring anti-coagulation therapy.
Treatments and study arms
bariatric surgery followed by total knee replacement
Procedure
The only intervention is the randomization of the priority of the 2 procedures.
Primary outcomes
Pain, mobility and quality of Life1 year
Knee Injury and Osteoarthritis Outcome Score (KOOS4)
Study locations
1 locations were listed when this page was built. The first 40 are shown.
Nova Scotia Health🇨🇦 Halifax, Nova Scotia, Canada
James Ellsmere, MDContact