Clinical trial

Neuronal and Behavioral Effects of an Implicit Priming Approach to Improve Eating Behaviors in Obesity

Recruiting now · Not applicable · 1 countries · Registry ID NCT05107908

Recruiting nowNot applicableInterventional

What this study is about

The purpose of this study is to determine how different behavioral interventions designed to alter food perceptions and behaviors affect brain responses to food, eating behaviors, and body weight.

A promising-looking record is not the same as confirmed eligibility. The study team must review the full criteria and current recruitment status.

Basic eligibility

Age18 Years to 65 Years
SexAll
Healthy volunteersAccepted
ConditionOverweight and Obesity

Full registry criteria

Inclusion Criteria: * 18-65 years old * BMI of 27 or greater Exclusion Criteria: * MRI contraindications (e.g., metal or electronic devices in the body) * Pregnancy

Treatments and study arms

Active Implicit Priming

Behavioral

Approximately 10-minute behavioral intervention

Control Implicit Priming

Behavioral

Approximately 10-minute behavioral intervention

Food Exposure Task

Behavioral

Approximately 10-30 minute behavioral intervention

Primary outcomes

Percent Change in Blood Oxygen Level Dependent (BOLD) Response to Visual Food Cues as Measured by Functional Magnetic Resonance ImagingBaseline, 12 weeks

Percent change in blood oxygen level dependent (BOLD) response from baseline to after the 12-week intervention while viewing visual food cues will be measured using functional magnetic resonance imaging (fMRI), focusing on insula, striatum, and prefrontal cortex.

Change in Food Image RatingsBaseline, 12 weeks

Food image ratings change from baseline to after the 12-week intervention. Food images are rated on "desire to eat" by visual analogue scale (0-100), with higher scores indicating greater desire to eat.

Change in Food IntakeBaseline, 12 weeks

Food intake change from baseline to after the 12-week intervention. Food intake will be measured as total calories consumed during an ad libitum meal.

Study locations

1 locations were listed when this page was built. The first 40 are shown.

University of Colorado Anschutz Medical Campus🇺🇸 Aurora, Colorado, United States
Christina Erpelding, BSContact
Kristina Legget, PhDContact
Jason Tregellas, PhDPrincipal Investigator