Clinical trial

Effects of Lifestyle Intervention on Childhood Outcomes in LGA Infants

Recruiting now · Not applicable · 1 countries · Registry ID NCT04661449

Recruiting nowNot applicableInterventional

What this study is about

Large-for-gestational-age (LGA) infants have a higher risk of metabolic disease later in life, and their postnatal growth in early childhood may be associated with long-term adverse outcomes. The purpose of this study is to explore whether comprehensive lifestyle intervention in the first year after birth in LGA infants will reduce the rate of overweight/obesity at childhood and improve neurodevelopmental outcomes and its possible mechanism.

A promising-looking record is not the same as confirmed eligibility. The study team must review the full criteria and current recruitment status.

Basic eligibility

Age1 Day to 1 Month
SexAll
Healthy volunteersNot accepted
ConditionChildhood Overweight

Full registry criteria

Inclusion Criteria: * term * large-for-gestational-age infants Exclusion Criteria: * major genetic disorder * congenital anomalies * severe digestive disease

Treatments and study arms

Comprehensive lifestyle intervention

Other

Feeding guidance: promoting exclusive breastfeeding and healthy diet (Pediatrician). Motor development assessment and guidance: Alberta Infant movement scale (AIMS) evaluation, guidance for motor development (Rehabilitation Therapist). Healthcare education: improvement of environmental exposure (Pediatrician).

Primary outcomes

Rate of overweight/obesity at 2 years oldat 2 years old

Weight and height will be combined to report BMI in kg/m\^2. According to the intergrowth-21st age-specific BMI standard issued in 2014, BMI ≥ 85th percentile is defined as overweight; BMI ≥ 95th percentile is defined as obesity

Rate of overweight/obesity at 7 years oldat 7 years old

Weight and height will be combined to report BMI in kg/m\^2. According to the intergrowth-21st age-specific BMI standard issued in 2014, BMI ≥ 85th percentile is defined as overweight; BMI ≥ 95th percentile is defined as obesity

Study locations

1 locations were listed when this page was built. The first 40 are shown.

Xinhua Hospital🇨🇳 Shanghai, Shanghai Municipality, China
Hongping Xia, DrContact