Clinical trial

GDM and Its Consequences in Mothers and Offsprings

Recruiting now · Not applicable · 1 countries · Registry ID NCT04529889

Recruiting nowNot applicableObservational

What this study is about

Gestational diabetes mellitus (GDM) is one of the most common disorders which occured during pregnancy. GDM is not only associated with short-term maternal and fetal adverse outcomes, but also related to a wide range of long-term consequences for both mother and child. The GDM and Its Consequences for mothers and offsprings (GDMCMO) aims to establish a cohort to follow both maternal and offsprings'short-term and long-term outcomes, including fetal malformations including congenital heart diseases, birth weight, preterm birth, caesarean section delivery, body growth and neurodevelopment after birth, obesity, type 2 diabetes and impaired insulin sensitivity and secretion, lung health and allergic diseases later in life for offspring, as well as future type 2 diabetes and cardiovascular risk factors for mother after delivery. Biological samples including blood and tissue samples of mothers and children are also collected during pregnancy and after delivery.

A promising-looking record is not the same as confirmed eligibility. The study team must review the full criteria and current recruitment status.

Basic eligibility

AgeNot listed to Not listed

SexAll

Healthy volunteersAccepted

ConditionGestational Diabetes Mellitus, Pregnancy Outcome, Neurodevelopment, Immune Development, Childhood Obesity, Host and Microbiome

Full registry criteria

Inclusion Criteria: 1. Pregnant women diagnosed with gestational diabetes mellitus 2. Pregnant women intended to eventually deliver in Guangzhou Women and Children's Medical Center 3. Permanent residents or families intended to remain in Guangzhou with their child for no less than 3 years Exclusion Criteria: 1. Women with pre-gestational diabetes mellitus 2. Women with chronic hypertension or kidney disease

Treatments and study arms

The registry does not list a named intervention.

Primary outcomes

Change of obesity status during childhood and adolescenceAt age of 6 months, 1 year, 3 years, 6 years, 12 years and 18 year

Weight in kilograms and height in meters were measured by nurses in clinic using standard tools. Weight and height will be combined to report BMI in kg/m\^2. Childhood obesity is defined as a BMI equal to or larger than the 95th percentile for age by sex based on WHO Child Growth Standards.

Study locations

1 locations were listed when this page was built. The first 40 are shown.

Guangzhou Women and Children's Medical Center🇨🇳 Guangzhou, Guangdong, China

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Qiu Qiu, MD,PhDContact

Email · Call 0086 20 38367160

Songying Shen, MScContact

Call 0086 20 38367159