Clinical trial

Technology-Supported Treatment of Sleep Apnea in Prediabetes

Active, not recruiting · Not applicable · 1 countries · Registry ID NCT04225507

Active, not recruitingNot applicableInterventional

What this study is about

Despite the efficacy of intensive lifestyle interventions in prediabetes, the incidence of diabetes is rising, and thus there is a critical need for additional strategies to prevent diabetes and to reduce its cardiovascular complications in this high-risk population. Sleep apnea is a highly common condition in prediabetes, but it has been mostly ignored and undertreated in current practice. The proposed study will be the first to assess whether adding CPAP (continuous positive air pressure) treatment to a lifestyle intervention improves cardiometabolic outcomes beyond that achieved with lifestyle alone (i.e. current standard of care) in high-risk individuals with prediabetes.

A promising-looking record is not the same as confirmed eligibility. The study team must review the full criteria and current recruitment status.

Basic eligibility

Age20 Years to 65 Years

SexAll

Healthy volunteersNot accepted

ConditionSleep Apnea, PreDiabetes, Overweight or Obesity

Full registry criteria

Inclusion Criteria: * Overweight or obese * Prediabetes * Sleep apnea Exclusion Criteria: * Diabetic * enrolled in a formal weight loss program * Any underlying disease likely to limit life span and/or increase risk of interventions

Treatments and study arms

Diet and exercise coaching

Behavioral

All participants will receive diet and exercise goals and coaching.

CPAP Treatment

Other

CPAP treatment for sleep apnea and CPAP education and adherence coaching.

Primary outcomes

Change from baseline 2-hour glucose levels at 6 monthsBaseline and at 6 months

Glucose levels will be measured at time=120min during oral glucose tolerance test

Study locations

1 locations were listed when this page was built. The first 40 are shown.

University of Chicago🇺🇸 Chicago, Illinois, United States

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