TrialGlobe

Clinical trial

Promotion of Weight Management

Active, not recruiting · Not applicable · 1 countries · Registry ID NCT04131647

Active, not recruitingNot applicableInterventional

What this study is about

The identification of intermittent fasting as an alternative method to traditional weight maintenance protocols could have a significant impact on preventing body weight regain common after successful weight loss, and potentially lead to a reduction in pharmaceutical and clinical costs related to the care of overweight and obese adults.

A promising-looking record is not the same as confirmed eligibility. The study team must review the full criteria and current recruitment status.

Basic eligibility

Age50 Years to 75 Years
SexAll
Healthy volunteersAccepted
ConditionOverweight

Full registry criteria

Inclusion Criteria: * Veteran * 50-75 years of age * BMI: 25-40 kg/m2 * Postmenopausal status for women Exclusion Criteria: * Uncontrolled diabetes (HbA1c \>10% or the current use of insulin) * Neurologic, musculoskeletal, or other condition that limits subject's ability to complete study physical assessments * Active inflammatory, autoimmune, infectious, hepatic, gastrointestinal, malignant, and psychiatric disease * Weight change within the past month of \>5 kg * Self-reported alcohol or drug abuse * Anti-coagulant medication for muscle biopsies only Impaired renal function (creatinine \> 1.5 mg/dl) History or evidence of serious liver disease (LFTs \> 2.5 x WNL)

Treatments and study arms

Weight Maintenance

Other

Following a 12-week weight loss and exercise program, subjects will participate in a weight maintenance program of Heart Healthy nutrition, walking, and resistance band exercise

Weight Maintenance + Intermittent Fasting

Other

Following a 12-week weight loss and exercise program, subjects will participate in a weight maintenance program of Heart Healthy nutrition, walking, resistance band exercise and intermittent fasting (2 small meals per day) one day per week for 24 weeks.

Primary outcomes

Change in Body WeightBaseline, after 12 weeks of weight loss+exercise, at 36-week weight maintenance, and 48-week follow-up

weight in kg

Study locations

2 locations were listed when this page was built. The first 40 are shown.

Baltimore VA Medical Center VA Maryland Health Care System, Baltimore, MD🇺🇸 Baltimore, Maryland, United States
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South Texas Health Care System, San Antonio, TX🇺🇸 San Antonio, Texas, United States
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