Clinical trial

Improving Glycemic Control With Electrical Stimulation

Recruiting now · Not applicable · 1 countries · Registry ID NCT03947697

Recruiting nowNot applicableInterventional

What this study is about

Once written consent is obtained, the participant will be provided with an accelerometer to be worn for 7 days to assess current physical activity levels. Subjects will be provided with a standardized diet (55/15/30% CHO/PRO/FAT) prior to collection of pre-intervention data of insulin sensitivity. Individuals will then participate in an 8-week electrical stimulation intervention (30min/day, 3x/week) and randomized into placebo/control, NMES, resistance training combined with NMES (RT +NMES), or resistance training (RT) group (n=15 per group), followed by collection of post-intervention data. The control group will receive electrical stimulation up to sensory level, the NMES group will receive stimulation up to tolerable intensity to induce visible muscle contraction, the RT+ NMES will receive stimulation up to tolerable intensity during resistance training, and the RT group will only receive exercise training. Pre-and post-intervention data includes measurements for body composition, resting metabolic rate, VO2max, insulin sensitivity, and comprehensive blood work.

A promising-looking record is not the same as confirmed eligibility. The study team must review the full criteria and current recruitment status.

Basic eligibility

Age18 Years to Not listed

SexAll

Healthy volunteersAccepted

ConditionObesity, Overweight, Insulin Resistance

Full registry criteria

Inclusion Criteria: * Overweight/Obese (BMI ≥25) * Sedentary Lifestyle: Physical Activity Level\<1.4 * Less than 150min/week of structured Exercise Exclusion Criteria: * Use of anti-hypertensive, lipid-lowering or insulin sensitizing medications * Excessive alcohol, drug abuse, smoking * Pregnant Women * Unwilling to adhere to the study Intervention

Treatments and study arms

Neuromuscular Electrical Stimulation (Sensory)

Device

Group will receive Electrical Stimulation up to sensory level

Neuromuscular Electrical Stimulation

Device

Group will receive Electrical Stimulation up to maximum tolerable level

Resistance Training

Other

Group will receive exercise training.

Primary outcomes

Glycemic Control8 weeks

Insulin Sensitivity will be measured through repeated blood sampling during an Oral Glucose Tolerance Test and Continuous Glucose Monitoring

Study locations

1 locations were listed when this page was built. The first 40 are shown.

University of Texas at El Paso🇺🇸 El Paso, Texas, United States

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Sudip R Bajpeyi, PhDContact

Email · Call 9157475461

Michelle Galvan, B.S.Sub Investigator

Jehu N Apaflo, M.S.Sub Investigator