Clinical trial

Differences in Sitting Versus Standing on Metabolic and Cardiovascular Measurements

Invitation only · Not applicable · 1 countries · Registry ID NCT03927638

Invitation onlyNot applicableObservational

What this study is about

This investigations examined the effect that posture has on metabolic and cardiovascular measurements. Further, it will explore the potential for body weight status or physical activity to influence these relationships. All subjects will complete a seated condition and a standing condition in a counterbalanced manner.

A promising-looking record is not the same as confirmed eligibility. The study team must review the full criteria and current recruitment status.

Basic eligibility

Age18 Years to 50 Years

SexAll

Healthy volunteersNot accepted

ConditionOverweight and Obesity

Full registry criteria

Inclusion Criteria: * healthy adult Exclusion Criteria: * Have a history of cancer, cardiac issues, hypertension, pulmonary disease, stroke, neurological or muscular dystrophy, uncontrolled diabetes, or any life threatening chronic conditions. * Are currently being treated for infectious mononucleosis, hepatitis, pneumonia, or other infectious diseases. * Are unable or unwilling to stand in one position continuously for 15-20 minutes at a time. * Use nicotine products, or non-contraceptive hormonal therapy (birth control is okay). * Are pregnant or trying to become pregnant. * Are not between 18 and 50 years of age.

Treatments and study arms

sit/stand

Behavioral

Subjects will be asked to both sit and stand during a single trial.

Primary outcomes

Heart RateApproximately 15 minutes in each condition (sitting and standing)

Using human non-invasive blood pressure continuous monitoring placed on the middle finger of the non-dominant hand will be used to measure heart rate based upon beat-by-beat finger pressure.

Systolic Blood Pressure (SBP)Approximately 15 minutes in each condition (sitting and standing)

Using human non-invasive blood pressure continuous monitoring placed on the middle finger of the non-dominant hand will be used to measure SBP based upon beat-by-beat finger pressure.

Diastolic Blood Pressure (DBP)Approximately 15 minutes in each condition (sitting and standing)

Using human non-invasive blood pressure continuous monitoring placed on the middle finger of the non-dominant hand will be used to measure DBP based upon beat-by-beat finger pressure.

Oxygen ConsumptionApproximately 15 minutes in each condition (sitting and standing)

Oxygen consumption will be measured using indirect calorimetry.

Carbon Dioxide ProductionApproximately 15 minutes in each condition (sitting and standing)

Carbon Dioxide will be measured using indirect calorimetry.

VentilationApproximately 15 minutes in each condition (sitting and standing)

Ventilation will be measured using indirect calorimetry.

Respiratory Exchange Ration (RER)Approximately 15 minutes in each condition (sitting and standing)

RER will be calculated using oxygen and carbon dioxide value measure from indirect calorimetry.

Study locations

1 locations were listed when this page was built. The first 40 are shown.

Montclair State University🇺🇸 Montclair, New Jersey, United States

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