Clinical trial

Effectiveness of Gradual Versus Rapid Weight Loss

Active, not recruiting · Not applicable · 1 countries · Registry ID NCT03776552

Active, not recruitingNot applicableInterventional

What this study is about

This randomized controlled trial aims to compare the 1-year effectiveness of an initial rapid weight loss (RWL) program and a gradual weight loss (GWL) program.

A promising-looking record is not the same as confirmed eligibility. The study team must review the full criteria and current recruitment status.

Basic eligibility

Age18 Years to Not listed
SexAll
Healthy volunteersAccepted
ConditionObesity

Full registry criteria

Inclusion Criteria: * • Willing and able to give informed consent for participation in the study * Living in the eastern part of Norway, mainly Oslo, Buskerud, Vestfold and Akershus * Understanding Norwegian language written and spoken easily * BMI ≥30.0 kg/m2 * Stable body weight (\<5 kg self-reported weight change) during the last 3 months before inclusion Exclusion Criteria: * • Pregnancy and breast-feeding mothers * Suspected non-compliance with regards to visits and/or diet * Severe chronic disease (endocrine disease, heart disease, neurological disease, lung disease, disease in the gastrointestinal tract, kidney disease, rheumatism or cancer).

Treatments and study arms

Rapid weight loss (RWL) program

Other

16-week rapid weight loss (RWL) program (8-week low energy diet (LED) followed by 8-week gradual increased energy intake) and a subsequent 36-week weight-maintenance follow-up

Gradual weight loss (GWL) program

Other

16-week gradual weight loss (GWL) program (moderate calorie restriction) and a subsequent 36-week weight-maintenance follow-up

Primary outcomes

Change in body weight from baseline to 12 monthsBaseline to 1-year

Percent total body weight loss (%TBWL) at 12 months follow-up

Study locations

1 locations were listed when this page was built. The first 40 are shown.

Vestfold Hospital Trust🇳🇴 Tønsberg, Norway