Clinical trial

Birth Cohort Study of China Medical University

Recruiting now · Not applicable · 1 countries · Registry ID NCT03561766

Recruiting nowNot applicableObservational

What this study is about

The CMUBCS is a birth cohort study located in Shenyang, China. Its initial aim is to facilitate research on understanding the interplay between genes and environmental factors on disease etiology. Data are collected regarding environmental factors, family and lifestyle, clinical experimental outcomes and imaging results of pregnant women and children from birth to 18 years old. Biological samples including blood and tissue samples are also collected from the children and their parents.

A promising-looking record is not the same as confirmed eligibility. The study team must review the full criteria and current recruitment status.

Basic eligibility

Age18 Years to Not listed

SexFemale

Healthy volunteersAccepted

ConditionTwin; Complicating Pregnancy, Advanced Maternal Age Pregnancy, Scarred Uterus, Overweight and Obesity

Full registry criteria

Inclusion Criteria: 1. Pregnant women, \<13 gestational weeks 2. Permanent residents or families intended to remain in Shenyang and surrounding areas 3. Pregnant women who are planned to be examined and delivered in Shengjing Hospital. Exclusion Criteria: 1. Pregnant women who refuse to take part in the study 2. Pregnant women have diseases that might affect the results of researches, including neuropsychiatric disorders.

Treatments and study arms

The registry does not list a named intervention.

Primary outcomes

Change of biometric parameter in centimeter of fetuses at the thirteenth week of gestational ageAt every week from the thirteenth week of gestational age to delivery of babies

Including head circumference, abdominal circumference, biparietal diameter, femur length of singleton and twin pregnancy

Weight in kilogram of neonateAt birth of neonate

Including singleton and twin pregnancy measured by nurses

Gene expression of husbands of pregnancy womenAt 13 weeks of gestational age

DNA methylation, histone acetylation etc. assessed by analyses of blood

Change of gene expression of pregnancy womenAt 13, 26 and 34 weeks of gestational age

DNA methylation, histone acetylation etc. assessed by analyses of blood

Result of Non-invasive Prenatal TestingFrom 12 to 22 weeks of gestational age

including singleton and twin pregnancy

Study locations

1 locations were listed when this page was built. The first 40 are shown.

Shengjing Hospital🇨🇳 Shenyang, Liaoning, China

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Shaowei Yin, PhDContact

Email · Call 86-18902458403

Jiajin Hu, PhDContact

Email · Call 86-18940287190