Clinical trial

Prevention of Coronary Heart Disease in Morbidly Obese Patients

Active, not recruiting · Not applicable · 1 countries · Registry ID NCT00626964

Active, not recruitingNot applicableObservational

What this study is about

The changes in risks of developing coronary heart disease in patients with morbid obesity after different weight loss interventions have not been extensively studied. The primary objective of this study is to investigate whether an intensive lifestyle intervention program in a tertiary care clinic (Spesialsykehuset for Rehabilitering) is comparable with a 7-week low-energy-diet followed by bariatric surgery in decreasing the risk of cardiovascular disease in these patients.

A promising-looking record is not the same as confirmed eligibility. The study team must review the full criteria and current recruitment status.

Basic eligibility

Age18 Years to 70 Years

SexAll

Healthy volunteersNot accepted

ConditionMorbid Obesity, Hypertension, Type 2 DM, Obstructive Sleep Apnea, Osteoarthrosis

Full registry criteria

Inclusion Criteria: * Morbidly Obese patients with BMI \> 40, or BMI \> 35 with comorbidity such as Hypertension, Obstructive Sleep Apnea, Weight Related Osteoarthrosis, Type 2 DM. Exclusion Criteria: * Participation in other weight loss program the last 12 months. Serious psychiatric conditions

Treatments and study arms

Bariatric Surgery

Procedure

Bariatric Surgery Treatment: Duodenal Switch, Gastric Sleeve or Gastric bypass.

Conservative Treatment:

Behavioral

Intensive Lifestyle Intervention Program

Primary outcomes

Arterial stiffness7 weeks and 1 year

Pulse wave velocity and augmentation index

Cardiovascular risk factors7 weeks and 1 year

Several biomarkers will be examined

Study locations

1 locations were listed when this page was built. The first 40 are shown.

Morbid Obesity Center, Vestfold Hospital Trust🇳🇴 Tønsberg, Norway

Open map