Condition

Clinical trials for Type 2 Diabetes Mellitus

Active public studies that list Type 2 Diabetes Mellitus as a condition.

23active studies

11recruiting now

19countries represented

201largest site network

Current studies

Status and location data reflect the registry snapshot built 2026-09-08. Verify the original record before contacting a site.

Recruiting nowPhase 3

A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With Obesity or Overweight and Type 2 Diabetes

Obesity or Overweight, Type 2 Diabetes MellitusCondition

Placebo, EnicepatideTreatment

Argentina, Australia193 locations

Hoffmann-La RocheSponsor

Updated 2026-08-14 · NCT07351058See eligibility →

Recruiting nowPhase 3

A Study of Once-daily Oral ASC30 to Evaluate the Efficacy and Safety in Adult Participants With Obesity or Overweight With Type 2 Diabetes

Obesity, OverweightCondition

ASC30 tablets A1, PlaceboTreatment

Czechia, Germany136 locations

Ascletis Pharma (China) Co., LimitedSponsor

Updated 2026-08-14 · NCT07743450See eligibility →

Recruiting nowPhase 3

A Study to Find Out if the Study Drug Elecoglipron Helps Adults With Type 2 Diabetes Mellitus by Comparing it With Semaglutide, a Medicine Already Used to Treat Type 2 Diabetes Mellitus

Type 2 Diabetes MellitusCondition

Elecoglipron, SemaglutideTreatment

Argentina, Australia201 locations

AstraZenecaSponsor

Updated 2026-07-14 · NCT07662213See eligibility →

Recruiting nowNot applicable

Automated Passive Case-Finding for Advanced Liver Fibrosis in MASLD: The LiverSeek Programme

Metabolic Dysfunction-Associated Steatotic Liver Disease, Liver FibrosisCondition

Intervention not listedTreatment

Spain1 locations

Hospital General Universitario Gregorio MarañonSponsor

Updated 2026-06-22 · NCT07658755See eligibility →

Recruiting nowNot applicable

Prevalence, Incidence and Risk Signature of Chronic Kidney Disease in Sub-Saharan Africa

Chronic Kidney Diseases, Type 2 Diabetes MellitusCondition

Intervention not listedTreatment

Tanzania1 locations

Swiss Tropical & Public Health InstituteSponsor

Updated 2026-04-29 · NCT05881447See eligibility →

Recruiting nowNot applicable

Clinical Management of Cardiovascular Risk Factors in Adult Patients: A Before-and-After Interventional Study

Cardiovascular Risk Factors, HypertensionCondition

Structured Cardiovascular Risk ManagementTreatment

Chile1 locations

Universidad Católica San Antonio de MurciaSponsor

Updated 2026-03-03 · NCT07447362See eligibility →

Recruiting nowNot applicable

Radiomics of Intra-abdominal and Subcutaneous Adipose Tissue Predict the Efficacy of Bariatric Surgery (RISABS)

Obesity, Type 2 Diabetes MellitusCondition

Intervention not listedTreatment

China1 locations

China-Japan Friendship HospitalSponsor

Updated 2025-08-03 · NCT06169033See eligibility →

Recruiting nowNot applicable

Puberty, Diabetes, and the Kidneys, When Eustress Becomes Distress (PANTHER Study)

Type 2 Diabetes Mellitus, Diabetic Kidney DiseaseCondition

Aminohippurate Sodium Inj 20%, Iohexol Inj 300 MG/MLTreatment

United States2 locations

Petter BjornstadSponsor

Updated 2025-03-24 · NCT05008276See eligibility →

Recruiting nowNot applicable

Date Seed Extract Effectiveness in Controlling Diabetes and Cardiovascular Risk in T2DM

Type 2 Diabetes Mellitus, ObesityCondition

Date Seed ExtractTreatment

Malaysia1 locations

Universiti Putra MalaysiaSponsor

Updated 2024-09-19 · NCT06590519See eligibility →

Recruiting nowPhase 4

Effects of Tirzepatide and Insulin Glargine on Glucolipid Metabolism and Brain Function in Patients With Type 2 Diabetes

Type 2 Diabetes MellitusCondition

Tirzepatide, Insulin GlargineTreatment

China1 locations

Nanjing First Hospital, Nanjing Medical UniversitySponsor

Updated 2022-09-23 · NCT05553093See eligibility →

Recruiting nowNot applicable

Nanshan Elderly Cohort Study

Hypertension, Type 2 Diabetes MellitusCondition

Intervention not listedTreatment

China2 locations

Sun Yat-sen UniversitySponsor

Updated 2018-06-26 · NCT03569735See eligibility →

Opening soonPhase 1

A Single-Dose Pharmacokinetic Study of HRS-4729 Injection in Healthy Participants and Patients With Renal Impairment

Overweight/Obesity, Metabolic Dysfunction-associated Steatotic Liver Disease/Steatohepatitis (MASLD/MASH)Condition

HRS-4729Treatment

China1 locations

Fujian Shengdi Pharmaceutical Co., Ltd.Sponsor

Updated 2026-09-08 · NCT07807059See eligibility →

Opening soonNot applicable

Vitamin D Status and Lipid Profile in Obese Adults With Type 2 Diabetes

Type 2 Diabetes Mellitus, ObesityCondition

Intervention not listedTreatment

Locations pending0 locations

Sinai UniversitySponsor

Updated 2026-07-27 · NCT07729553See eligibility →

Opening soonNot applicable

Safety and Effectiveness of Tirzepatide in Patients With Obesity at Hospital de Clínicas, Paraguay

Obesity, Type 2 Diabetes MellitusCondition

Tirzepatide (T.G.)Treatment

Paraguay1 locations

LABORATORIOS INDUFARSponsor

Updated 2026-03-25 · NCT07492563See eligibility →

Active, not recruitingNot applicable

Preventing Type 2 Diabetes in Black Emergent Adult

Type 2 Diabetes Mellitus, Binge-Eating DisorderCondition

Appetite Awareness Training (AAT), Diabetes Prevention Program (DPP)Treatment

United States1 locations

University of North Carolina, Chapel HillSponsor

Updated 2026-08-25 · NCT06848244See eligibility →

Active, not recruitingPhase 1

A Study to Evaluate the Effect of RO7204239 on Insulin Sensitivity and Muscle Composition in Participants With Type 2 Diabetes Mellitus (T2DM) and Overweight or Obesity

Type 2 Diabetes Mellitus, ObesityCondition

Placebo, RO7204239Treatment

Germany1 locations

Hoffmann-La RocheSponsor

Updated 2026-07-09 · NCT07137585See eligibility →

Active, not recruitingPhase 2

A Study to Compare Different Doses of RO7795081 With a Placebo or Semaglutide in People With Type 2 Diabetes

Type 2 Diabetes MellitusCondition

RO7795081, SemaglutideTreatment

Hungary, Poland50 locations

Hoffmann-La RocheSponsor

Updated 2026-07-07 · NCT07112872See eligibility →

Active, not recruitingNot applicable

The TRIABETES - ARMMS-T2D Study: A Randomized Trial to Compare Surgical and Medical Treatments for Type 2 Diabetes

Type 2 Diabetes Mellitus, ObesityCondition

Roux-en-Y Gastric Bypass Surgery, Laparoscopic Adjustable Gastric BandingTreatment

United States1 locations

University of PittsburghSponsor

Updated 2026-06-11 · NCT01047735See eligibility →

Active, not recruitingPhase 2

Semaglutide Effects in Obese Youth With Prediabetes/New Onset Type 2 Diabetes and Metabolic Dysfunction-Associated Steatotic Liver Disease

Type 2 Diabetes Mellitus, Impaired Glucose ToleranceCondition

Semaglutide Pen Injector, PlaceboTreatment

United States1 locations

Yale UniversitySponsor

Updated 2026-04-15 · NCT05067621See eligibility →

Active, not recruitingNot applicable

Impact of Metabolic Health on Sperm Epigenetic Marks in Humans

Overweight, Type 2 Diabetes MellitusCondition

Lifestyle Intervention, No InterventionTreatment

United States1 locations

Joslin Diabetes CenterSponsor

Updated 2026-02-06 · NCT03860558See eligibility →

Active, not recruitingNot applicable

Early Sleeve Gastrectomy In New Onset Diabetic Obese Patients

Type 2 Diabetes MellitusCondition

LSG, CMTTreatment

Italy2 locations

Azienda Ospedaliera Santa Maria, Terni, ItalySponsor

Updated 2026-01-26 · NCT02488733See eligibility →

Active, not recruitingNot applicable

Winter-Swimming and Brown Adipose Tissue Activity in Middel-aged Obese Subjects (WinterBAT).

Adipose Tissue, Brown, Brown Adipose TissueCondition

Winter Swimming, Control groupTreatment

Denmark1 locations

Kristian KarstoftSponsor

Updated 2025-08-17 · NCT03541096See eligibility →

Active, not recruitingPhase 1, Phase 2

Renal HEIR Study: Renal Hemodynamics, Energetics and Insulin Resistance in Youth Onset Type 2 Diabetes Study

Type 2 Diabetes Mellitus, ObesityCondition

Aminohippurate Sodium Inj 20%, Iohexol Inj 300 MG/MLTreatment

United States1 locations

University of Colorado, DenverSponsor

Updated 2023-08-15 · NCT03584217See eligibility →

Related conditions

Obesity1,102 Obesity & Overweight220 Overweight205 Overweight and Obesity130 Type 2 Diabetes108 Hypertension107

How current is this page?

The page is rebuilt from the public registry feed. Each trial card shows the registry update date. Recruitment can still change between builds.

Does appearing here mean I qualify?

No. These pages are discovery indexes. Only a study team can confirm eligibility after reviewing the complete protocol criteria.